In the first stage with an uphill finish, the peloton rode up the Pico Jano in the pouring rain and dense fog. "I didn't have the legs to go with the best in that stage”, Roglic said, referring to the moment Remco Evenepoel and Enric Mas rode away. "I decided to give everything until the finish line. I did a lot of the work in the pursuit. Although we lost some time today, Madrid is still far away. Hopefully we can reclaim some time in the coming days. The competition is strong. We were aware of this going into this stage. I feel good and I am ready to fight. I am looking forward to the coming days", the Slovenian concluded.

Sports director Grischa Niermann had seen a challenging sixth stage of the Vuelta. "We had quite bad weather, especially on top of the climbs. But that is also part of the race. Eight kilometres from the finish line, Primoz was unable to keep up with Evenepoel and Mas. From that point on, it was critical to minimize the damage. Of course we had hoped for a different outcome, but nothing is lost. The Vuelta is still long. We have to conclude that today was a lesser day for us. Hopefully the roles will be reversed in the coming days."